Both low and high dose intravaginal estradiol cream caused a greater It is well absorbed through the vaginal epithelium and circumvents the “first pass”.
Martin PL, Yen SS, Burnier AM, Hermann H. Systemic absorption and sustained effects of two estrogen vaginal cream preparations (Premarin.
My doctor prescribed a low-dose vaginal estrogen cream, applied twice a to determine how much estrogen is absorbed into the bloodstream.
Vaginal estrogen delivers a low dose of hormone to the local vaginal tissue with minimal systemic absorption. Vaginal creams include a 17β-estradiol vaginal.
Systemic absorption and sustained effects of two estrogen vaginal cream preparations (Premarin and Estrace) were measured in 29 postmenopausal women.